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M94A0338.TXT
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1994-10-08
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Document 0338
DOCN M94A0338
TI An electron-lucent region within the virion distinguishes HIV-1 from
HIV-2 and simian immunodeficiency virus.
DT 9412
AU Yu QC; Matsuda Z; Yu X; Ito S; Essex M; Lee TH; Department of Cancer
Biology, Harvard School of Public Health,; Boston, Massachusetts 02115.
SO AIDS Res Hum Retroviruses. 1994 Jun;10(6):757-61. Unique Identifier :
AIDSLINE MED/94355123
AB Ultrastructural comparisons of immature or budding particles of human
immunodeficiency virus (HIV) types 1 and 2 and simian immunodeficiency
virus of macaques (SIVmac) revealed no significant difference between
these genetically distinct, but related, viruses. However, a region
encompassing the core of mature HIV-1 virions was found to be more
electron lucent than that observed in HIV-2 and SIVmac. This
ultrastructural distinction cannot be attributed to HIV-1-specific vpu,
HIV-2/SIV-specific vpx, or virion-associated vpr gene products.
DE Comparative Study HIV-1/*ULTRASTRUCTURE HIV-2/*ULTRASTRUCTURE
Microscopy, Electron Support, U.S. Gov't, Non-P.H.S. Support, U.S.
Gov't, P.H.S. SIV/*ULTRASTRUCTURE JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).